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Εταιρικά Νέα :
- Calyculin A - Cell Signaling Technology
Calyculin A is a more potent phosphatase inhibitor than Okadaic acid (2) As shown by Western blot, treatment of cells with 100 nM Calyculin A for 30 minutes induces threonine phosphorylation, detected by Phospho-Threonine-Polyclonal Antibody #9381
- Calyculin A ((-)-Calyculin A) | Phosphatase Inhibitor | MedChemExpress
Calyculin A ( (-)-Calyculin A) is a potent and cell-permeable protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A) inhibitor with IC50 s of 2 nM and 0 5-1 nM, respectively [1] Calyculin A (1-10 nM; 24 hours) induces cytotoxicity in MG63 cells in a dose-dependent manner [2]
- Calyculin A from Discodermia Calyx Is a Dual ActionToxin that Blocks . . .
Calyculin A (Caly A) is cell permeable toxin widely used in cell biology research as an inhibitor of type 1 and type 2A protein Ser Thr phosphatases of the PPP family Here we tested effects of low concentrations of Caly A on proliferation of human cancer and non-cancer cell lines
- Calyculin A, Discodermia calyx - MilliporeSigma
Calyculin A, Discodermia calyx, Calyculin A, CAS 101932-71-2, is a cell-permeable inhibitor of protein phosphatase 2A (IC₅₀ = 0 5-1 nM) and protein phosphatase 1 (PP1; IC₅₀ = 2 nM)
- Calyculin A - an overview | ScienceDirect Topics
Calyculin A (CyA) is an octamethylpolyhydroxylated C-28 fatty acid linked to two γ-amino acids and esterified with phosphate It is cell membrane permeable In additionto CyA, seven other related compounds have been isolated
- Calyculin A | CAS 101932-71-2 | SCBT - Santa Cruz Biotechnology
Calyculin A, a marine toxin found in Disodermia calyx, is a structurally distinct inhibitor of protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A-C) It has been shown that calyculin A displays inhibitory properties towards the endogenous phosphatase of smooth muscle myosin B and induces contraction in the muscle fibers
- Calyculin A | Protein Ser Thr Phosphatases | Tocris Bioscience
Calyculin A is a potent and selective cell-permeable inhibitor of protein phosphatase 1 (IC 50 = 0 3 - 0 7 nM) and protein phosphatase 2A (IC 50 = 0 5 - 1 nM) Displays > 10,000,000-fold selectivity over PP2B and PP2C
- Calyculin A - Thermo Fisher Scientific
Calyculin A is a structurally unique marine toxin with potent and specific protein phosphatase inhibiting activity This compound inhibits PP2A with similar potency to okadaic acid, but inhibits PP1 with a 10- to 100-fold greater potency Some of the effects observed with this
- Calyculin A, an inhibitor of protein phosphatases, a potent tumor . . .
Like okadaic acid, calyculin A induced ornithine decarboxylase in mouse skin and hyperphosphorylation of a Mr 60,000 protein in human papilloma virus type 16-transformed human keratinocytes
- Calyculin A | Purity gt;98% (HPLC) | CAS 101932-71-2 | Alomone Labs
High purity Calyculin A (#C-100) is a potent protein phosphatase 1 protein phosphatase 2 inhibitor from Alomone Labs A natural biologically active compound New lots biologically tested
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