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- ITGAM Gene - GeneCards | ITAM Protein | ITAM Antibody
ITGAM (Integrin Subunit Alpha M) is a Protein Coding gene Diseases associated with ITGAM include Systemic Lupus Erythematosus 6 and Neutropenia, Severe Congenital, X-Linked Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and Integrin Pathway
- ITGAM protein expression summary - The Human Protein Atlas
Selective cytoplasmic expression in subset of immune cells and glial cells Main subcellular location based on data generated in the subcellular section of the Human Protein Atlas
- ITGAM integrin subunit alpha M [ Homo sapiens (human) ]
A stable-isotope labeling by amino acids in cell culture coupled with mass spectrometry-based proteomics identifies upregulation of integrin, alpha M (ITGAM, CR3A) expression by HIV-1 Vpr in Vpr transduced macrophages
- The CD11b-integrin (ITGAM) and systemic lupus erythematosus
Variations at the ITGAM gene, which encodes for the CD11b chain of the Mac-1 (alphaMbeta2; CD11b CD18; complement receptor-3) integrin, is one of the strongest genetic risk factors for systemic lupus erythematosus (SLE)
- ITGAM Gene: Function, Role in Immunity, and Disease
Explore the ITGAM gene, encoding the integrin alpha M protein Learn about its role in immune response, inflammation, and its association with various diseases
- Itgam - Abcam
Integrin ITGAM ITGB2 is also a receptor for fibrinogen, factor X and ICAM1 It recognizes P1 and P2 peptides of fibrinogen gamma chain Regulates neutrophil migration
- ITGAM基因的功能与作用机制解析 - 八方基因
总的来说， ITGAM 是一个多功能的基因，在细胞粘附、免疫反应和炎症调控中起着至关重要的作用。 了解其功能和作用机制，不仅有助于我们理解基本的生物学过程，也为开发新的治疗方法提供了潜在的靶点。 本文将详细介绍ITGAM基因的功能与作用机制，探讨其在细胞粘附、免疫反应、炎症调控等过程中的关键作用，并分析其与多种疾病的关系。 ITGAM基因概述 首先，让我们来了解一下ITGAM基因 。 这个基因编码的是一个叫做integrin subunit alpha M 的蛋白质，也被称为MAC-1 或CD11b 。 它位于人类染色体的16p11 2位置，属于一个大家族，包括CD molecules
- ITGAM: A Pivotal Regulator in Macrophage Dynamics and Cardiac Function . . .
The significant upregulation of Itgam in MAC2 post-CLP indicates a dynamic shift in this subtype's role during SIC progression ITGAM, also known as CD11b, synergizes with the beta 2 chain (ITGB2) to constitute a leukocyte-specific integrin, commonly recognized as Mac-1
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