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- Propofol-related Infusion Syndrome • LITFL • CCC Pharmacology
Propofol-related Infusion Syndrome (PRIS) is a life-threatening condition characterised by acute refractory bradycardia progressing to asystole and one or more of:
- PRIS | User Login
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- Propofol Infusion Syndrome in Adults: A Clinical Update - PMC
PRIS is a rare but extremely dangerous complication of propofol administration with a high mortality Certain risk factors for the development of PRIS are described, such as inappropriate propofol doses and durations of administration, carbohydrate depletion, severe illness, and concomitant administration of catecholamines and glucocorticosteroids
- MikeArticle_MikeArticle - University of Virginia School of Medicine
Propofol-related infusion syndrome (PRIS) is a rare yet often fatal syndrome that has been observed in critically ill patients receiving propofol for sedation PRIS is charac-terized by severe unexplained metabolic acidosis, arrhythmias, acute renal failure, rhabdomyolysis, hyperkalemia, and cardiovascular collapse
- Propofol Infusion Syndrome? – ResusNation
Propofol infusion syndrome (PRIS) is a rare and potentially fatal condition that was first reported in children in 1990 It is characterized by profound metabolic acidosis and bradycardia which may ultimately lead to cardiac arrest
- Propofol Related Infusion Syndrome - DFW Anesthesia Professionals
Propofol-related infusion syndrome (PRIS) is a rare but severe condition associated with the administration of propofol, an anesthetic commonly used for sedation in medical procedures First identified in the 1990s, PRIS can be fatal if not recognized and treated promptly
- Successful treatment of propofol-related infusion syndrome in . . .
Propofol is widely used to sedate agitated patients in intensive care units However, it can cause a rare but fatal complication, propofol-related infusion syndrome (PRIS) The pathophysiology of PRIS is not clear, and there is no definitive diagnosis and treatment
- Propofol infusion syndrome - PubMed
The clinical features of propofol infusion syndrome (PRIS) are acute refractory bradycardia leading to asystole, in the presence of one or more of the following: metabolic acidosis (base deficit > 10 mmol l (-1)), rhabdomyolysis, hyperlipidaemia, and enlarged or fatty liver
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