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- Transthyretin - Wikipedia
Transthyretin (TTR or TBPA) is a transport protein in the plasma and cerebrospinal fluid that transports the thyroid hormone thyroxine (T 4) and retinol to the liver This is how transthyretin gained its name: trans ports thy roxine and retin ol
- Transthyretin Amyloidosis (ATTR-CM): Types, Causes, Treatment
Transthyretin amyloidosis (ATTR-CM) occurs when your liver produces faulty transthyretin (TTR) proteins Clumps of these abnormal proteins (called fibrils) build up in your heart’s main pumping chamber
- A Narrative Review of the Role of Transthyretin in Health and . . .
Transthyretin is a highly conserved protein that transports the thyroid hormone thyroxine and the retinol-binding protein bound to retinol (vitamin A) Mutations in TTR are associated with ATTR amyloidosis, a progressive, debilitating, and ultimately fatal disease
- Transthyretin Amyloid Cardiomyopathy (ATTR-CM) | American . . .
Transthyretin (trans-thy-re-tin) amyloid cardiomyopathy (ATTR-CM) is an underdiagnosed and potentially fatal disease of the heart muscle In ATTR-CM, a protein called transthyretin that normally circulates in the bloodstream becomes misshapen and builds up in the heart, nerves and other organs
- The role of transthyretin in cell biology: impact on human . . .
Transthyretin (TTR) is an extracellular protein mainly produced in the liver and choroid plexus, with a well-stablished role in the transport of thyroxin and retinol throughout the body and brain
- TTR gene - MedlinePlus
Transthyretin is produced primarily in the liver, and a small amount of this protein is produced in an area of the brain called the choroid plexus and in the light-sensitive tissue that lines the back of the eye (the retina) Variants (also called mutations) in the TTR gene cause transthyretin amyloidosis
- Transthyretin: Its function and amyloid formation - ScienceDirect
Transthyretin (TTR), one of the major amyloidogenic proteins in systemic amyloidosis, is mainly synthesized in the liver but also in the choroid plexuses of the brain (Bezerra et al , 2020)
- Transthyretin | definition of transthyretin by Medical dictionary
A protein component of plasma having a molecular weight of about 55,000 and containing 1 3% carbohydrate; estimated plasma concentration is 0 3 g per 100 mL; abnormal levels of prealbumin are found in cases of familial amyloidosis Synonym (s): transthyretin 2
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