Guidelines for HIV post-exposure prophylaxis Timely access to PEP is the most crucial factor in PEP effectiveness PEP is most effective when initiated as soon as possible, ideally within 24 hours and no later than 72 hours after exposure
Clinical Guidance for PEP | HIV Nexus | CDC If the most recent recurring exposure was within the 72-hour window before evaluation, PEP may be indicated, and the patient can be prescribed PrEP after taking PEP for 28 days
Post-Exposure Prophylaxis (PEP) | NIH - HIVinfo Post-exposure prophylaxis (PEP) refers to a short course (28 days) of HIV medicines that are taken after a possible exposure to prevent HIV infection PEP must be started within 72 hours after a possible exposure to HIV
PEP to Prevent HIV Infection - Clinical Guidelines Program After an exposure has occurred, HIV infection can be prevented with rapid administration of ARV medications as PEP The first dose of PEP should be administered within 2 hours of an exposure (ideal) and no later than 72 hours after an exposure
Core Concepts - Occupational Postexposure Prophylaxis - HIV HIV Testing: Follow-up HIV testing at 4–6 weeks postexposure is recommended only if the health care personnel exposed to HIV initiated the occupational HIV PEP more than 24 hours after a single exposure, or for those who missed any doses of HIV PEP medications
EACS: Post-exposure Prophylaxis (PEP) post-exposure prophylaxis PEP is no longer recommended post-exposure prophylaxis PEP to be started ideally < 4 hours after the exposure, and no later than 72 hours
PEP – Emergency HIV Prevention After a Possible Exposure PEP (Post‑Exposure Prophylaxis) is a 28‑day course of HIV medication you start after a possible exposure It must begin within 72 hours —the sooner the better; every hour counts
PEP Quick Guide for Bloodborne Pathogen Exposures Additionally, updated CDC USPHS Guidelines suggest that interim testing (4-6 weeks post-exposure) may be deferred for exposed persons who initiated PEP within 24 hours of exposure and did not miss any PEP doses