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- Oxybate Treatment for Cataplexy and EDS in Narcolepsy |XYREM®
XYREM® (sodium oxybate) is approved for use in adults and children ages 7 and older to help treat cataplexy and EDS in narcolepsy See XYREM® prescribing information BOXED Warning about serious side effects, CNS depression, misuse and abuse
- Xyrem: Uses, Dosage, Side Effects, Warnings - Drugs. com
Xyrem’s mechanism of action for narcolepsy is thought to involve binding to GABA B and GHB receptors to enhance deep sleep at night, which helps to reduce EDS The exact way Xyrem works is unknown (see How does Xyrem work for narcolepsy?) Xyrem belongs to the class of medicines known as central nervous system (CNS) depressants
- XYREM - Sodium Oxybate Treatment for Cataplexy and EDS in . . .
Learn about XYREM® (sodium oxybate oral solution), and how it can help your narcolepsy patients’ cataplexy and excessive daytime sleepiness (EDS) symptoms See XYREM® prescribing information BOXED Warning about serious side effects, CNS depression, misuse, and abuse
- Effects of Oxybate on Sleep, Sleep Architecture, and . . .
Sleep disturbances in narcolepsy encompass self-reported sleep quality, sleep architecture, and DNS DNS is associated with frequent sleep stage shifts and awakenings arousals on polysomnography Sodium oxybate (SXB; Xyrem ® ), dosed twice nightly, is approved to treat excessive daytime sleepiness and cataplexy in patients with narcolepsy
- Xyrem: Side effects, use for narcolepsy, dosage, and more
Xyrem and obstructive sleep apnea Clinical trials showed that for people with obstructive sleep apnea who took 9 g of Xyrem each night, there was no increase in how severe their sleep apnea was
- Implications of Oxybate Dosing Regimen for Sleep, Sleep . . .
Narcolepsy is associated with disrupted nighttime sleep (DNS) Sodium oxybate (SXB; Xyrem®), administered twice nightly, is indicated for the treatment of cataplexy and excessive daytime sleepiness in patients 7 years or older with narcolepsy
- Sodium Oxybate (Xyrem) - Uses, Side Effects, and More
Find patient medical information for Sodium Oxybate (Xyrem) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings It can also cause sleep
- Xyrem (Sodium oxybate) for Narcolepsy | MyNarcolepsyTeam
The FDA-approved label for Xyrem lists common side effects including nausea, dizziness, vomiting, drowsiness, involuntary urination, and tremors Rare but serious side effects listed for Xyrem include central nervous system depression (which can slow breathing and heart rate), depression, suicidality, confusion, anxiety, and sleep walking
- Xywav or Xyrem: What’s the Difference? - Sleep Review
For more than a decade and a half, Xyrem (sodium oxybate) has been prescribed to patients with narcolepsy who experience cataplexy or excessive daytime sleepiness It was the only US Food and Drug Administration (FDA)-approved therapy for the treatment of cataplexy (though sleep physicians also prescribe other drugs off-label to alleviate the
- How does Xyrem work for narcolepsy? - Drugs. com
Xyrem's mechanism of action for narcolepsy is thought to involve binding to GABA B and GHB receptors which enhances delta wave activity, improving the quality and quantity of deep sleep; however, the exact way it works is unknown By taking Xyrem at night, the quality and quantity of deep sleep is improved, which reduces the number of sleeping
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